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1.
Farmacia ; 70(3):386-390, 2022.
Article in English | Web of Science | ID: covidwho-1929072

ABSTRACT

Coronavirus disease 19 (COVID-19) pandemic is at the moment the main topic of interest regarding medical science and research. Responsible for the disease is a novel coronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accountable for over 118 million cases and a total of 2.61 million deaths worldwide (July 2020). Drug treatment for infected COVID-19 patients represents a difficult task, since there is no currently licensed specific antiviral for SARS-CoVs, the clinical approach of these patients remains the symptomatic one and also providing supportive care if needed. The clinical approach becomes more of a challenge especially if one has a co-existing psychiatric illness under psychotropic treatment. This concern is raised due to potential drug-to-drug interactions (DDIs) between antiviral agents and psychotropics, not only by common metabolic pathways regarding P450 cytocromial enzymes but also by pharmacological synergism regarding common adverse effects. Thus, we searched to identify studies published in PubMed medical database to support clinical practice in these situations and found that mostly all main psychotropics are implied in DDIs with the antivirals used to treat COVID-19 infection. Therefore, the clinical approach in treating COVID-19 patients with antiviral agents remains a challenge especially for those who have a comorbid psychiatric illness and are under treatment with psychotropics.

2.
European Psychiatry ; 64(S1):S315, 2021.
Article in English | ProQuest Central | ID: covidwho-1357284

ABSTRACT

IntroductionCovid-19 pandemic represents o very stressfull period for many individuals. Intimate partner violence is typically experienced by women but can also be experienced by men. During quarantine due to the Covid-19 pandemic, the risk for domestic violence increased.ObjectivesThe aim of this study was to compare domestic violence durind two different periods - 14.03.2019-30.09.2019 and the same period of the year 2020.MethodsWe analyzed the data base of the Legal Institut from Cluj-napoca and we selected the cases with domestic violence.ResultsThe violent behaviour incresed durind 2020. Due to the feelings of frustration and agitation, agression arises with possible trasgenerational transmission of trauma and violence.ConclusionsTaking into consideration that Covid19 pandemic is a very stressfull period for all individuals, a need of programms aimed to prevent acts of domestic violence and to achieve accurate assessment of multiple domains of abuse (psychological, physical, sexual) provided by psychologists, psychiatrists, social and legal services emerged.

3.
European Psychiatry ; 64(S1):S260, 2021.
Article in English | ProQuest Central | ID: covidwho-1357153

ABSTRACT

IntroductionThe Covid-19 pandemic has a profound impact on all domains of day to day life, forcing individuals to make substancial change in the way of living. Such change is known to cause an important psychological distress, and in some persons evidencing silent disorders among apparently functional individuals. Good coping mechanisms and resilience can be the key to overpass this difficult period.ObjectivesThe aim of this study is to evaluate the coping mechanisms and resilience that Romanian psychiatric trainees used during Covid19 pandemic.MethodsWe developed an online questionnaire. We included questions about different socio-demographical variables and about coping mechanisms (using COPE scale), resilience (using Connor-Davidson Resilience Scale) and quality of life (using QoL Scale).ResultsThe preliminary data show that staying busy, seeking social support and having a positive minset are emotion-focused coping strategies present in individuals who overpass easier this period.ConclusionsThe Covid-19 pandemic is creating significant distress and impairment in functioning, but individuals who have good psychological mechanisms and who are more adaptable are less vulnerable during Covid-19 pandemic. Future research should build upon these findings to better understand coping mechanisms during crises and also social policies should be developed to acknowledge the variable needs in adults.

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